Monday, October 19, 2009
Rich Smith :: Townhall.com Columnist
This Just In: Upgrades and Downgrades
by Rich Smith
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At The Motley Fool, we poke plenty of fun at Wall Street analysts and their endless cycle of upgrades, downgrades, and "initiating coverage at neutral." So you might think we'd be the last people to give virtual ink to such "news." And we would be -- if that were all we were doing.

But in "This Just In," we don't simply tell you what the analysts said. We'll also show you whether they know what they're talking about. To help, we've enlisted Motley Fool CAPS, our tool for rating stocks and analysts alike. With CAPS, we track the long-term performance of Wall Street's best and brightest -- and its worst and sorriest, too.

And speaking of the worst ...
Geron (Nasdaq: GERN) investors have endured-slash-enjoyed a wild ride this year. Their stock exploded with January's news that the FDA had cleared the company's GRNOPC1"hESC-based therapeutic candidate" for use in a human clinical trial to treat patients with acute spinal cord injuries. Fast forward a few months, however, and the stock imploded on August's news that the selfsame FDAwas suspending clinical trials of the treatment. And now they can thank Wall Street banker Merriman Curhan Fordfor their latest upward swing.

Merriman thinks Geron could as much as double off today's price, primarily in response to successful data on GRN163L, a treatment that targets cancer agent telomerase "through direct inhibition and through an immunotherapy (vaccine) approach." Reports Merriman, GRN163L is currently undergoing "multiple clinical trials and represents a promising new cancer therapeutic." Oh, and incidental to GRN163L, Merriman notes that: "Geron also is poised to be a key leader in the embryonic stem cell arena." Put these two facts in a centrifuge and set it on high -- the result that spins out is a "buy," says Merriman.

Is this spinner a winner?
I'm not so sure. Investing in profitless biotechs like Geron is always a hi-stakes endeavour, and one practically guaranteed to fill a portfolio with as many big losers and big winners -- as Merriman's record shows:

Stock

Merriman Says

CAPS Says

Merriman's Picks Beating
(Lagging) S&P by

Pharmasset

Outperform

**

54 points

Abraxis BioScience

Outperform

***

32 points

American Oriental Bioengineering
(NYSE: AOB)

Outperform

***** Continued...

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About The Author

Rich Smith is a business writer with the Motley Fool.

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